Athletic Performance

Mitochondria are as fascinating as they are essential: They have their own set of DNA. Even the growth of new mitochondria has a name: “mitochondrial biogenesis.” Mitochondrial biogenesis is key to maintaining youthful cellular energy production. PQQ also supports mitochondrial biogenesis and encourages healthy cellular energy levels in 3 distinct ways:

Mitochondrial DNA & antioxidant protection

The enormous amount of cellular energy generated within mitochondria also exposes them to constant free radical activity. Fortunately, PQQ is a potent antioxidant, offering powerful free radical protection and maximum support for cellular energy production at the same time.⁵

Mitochondria possess their own DNA, which is different from the DNA found in a cell’s nucleus. Unfortunately, mitochondrial DNA is more vulnerable to mutations than nuclear DNA. PQQ's antioxidant potency and favorable gene expression profile help to support delicate mitochondrial DNA against oxidation.

Favorable gene expression

PQQ activates genes that promote the formation of new mitochondria.¹⁰ PQQ also beneficially interacts with genes directly involved in mitochondrial health. These same genes also support healthy sugar and fat metabolism, youthful cellular proliferation and more.^6,7,11

Other potential whole-body health benefits

PQQ may support quality, restful sleep, heart health and cognitive function, by itself and in combination with CoQ10.^8-13 Plus, when taken with CoQ10, PQQ promotes memory, attention and cognition in maturing individuals.

NIAGEN® nicotinamide riboside

NIAGEN® is a patented, clinically studied form of nicotinamide riboside, a compound that helps increase cellular levels of the NAD⁺ coenzyme. This is important because the NAD⁺ coenzyme is necessary for creating adenosine triphosphate (ATP), the compound your body uses to create cellular energy.

In a randomized controlled trial, older adults taking 250 mg of nicotinamide riboside a day experienced a 40% increase in NAD⁺ levels after just 30 days. Evidence from pre-clinical studies indicates that increasing NAD⁺ also encourages healthy metabolic and cognitive function. This formula contains 300 mg of NIAGEN® in every vegetarian capsule.

Promotes healthy aging and longevity

NAD⁺ Cell Regenerator™ also promotes the activity of sirtuin (SIRT1 and SIRT3), essential proteins that work with NAD⁺ to promote healthy aging. It also enhances production and function of mitochondria, the cellular powerhouses that provide the energy you need to thrive.

NIAGEN® nicotinamide riboside

NIAGEN® is a patented, clinically studied form of nicotinamide riboside, a compound that helps increase cellular levels of the NAD+ coenzyme. This is important because the NAD+ coenzyme is necessary for creating adenosine triphosphate (ATP), the compound your body uses to create cellular energy.

In a randomized controlled trial, older adults taking 250 mg of nicotinamide riboside a day experienced a 40% increase in NAD+ levels after just 30 days. Evidence from pre-clinical studies indicates that increasing NAD+ also encourages healthy metabolic and cognitive function.

Promotes healthy aging and longevity

NAD+ Cell Regenerator™ also promotes the activity of sirtuin (SIRT1 and SIRT3), essential proteins that work with NAD+ to promote healthy aging. It also enhances production and function of mitochondria, the cellular powerhouses that provide the energy you need to thrive.

HMB for muscle protein balance and exercise performance

Healthy muscles depend on the natural balance between two complementary processes: anabolism, where muscle is created, and catabolism, where muscle is deconstructed. But as we age, our body's ability to build new muscle slows down—even when it has the necessary proteins and amino acid “building blocks” to do so.^5,6

The result is a decline in muscle mass and strength. HMB has beneficial effects on muscle mass by helping to preserve the structural integrity of your muscles and supporting muscle growth.^7,8 HMB also supports exercise performance during both resistance and endurance training.^9-16

HMB in clinical studies

HMB and Bed Rest: Prolonged bed rest can result in loss of muscle mass. In a randomized placebo-controlled study, men and women were confined to bed rest for 10 days, followed by eight weeks of resistance training rehabilitation. Each group took either 3 g a day of HMB or a placebo for 5 days prior to bed rest, up until the end of the study. The placebo group lost lean mass during bed rest, but those given HMB during bed rest showed no such decline.¹⁷

HMB and Resistance Training: In a randomized, placebo-controlled trial, men and women received 3 g a day of HMB, or a placebo and trained for 4 weeks. At the end of the study, the HMB group had a greater increase in upper body strength than the placebo group.¹³ In another clinical study, supplementation with 3 g a day of HMB for 9 weeks provided a substantial benefit to lower-body strength when combined with resistance training.¹⁴ 

HMB and Older Adults: In a 24-week, randomized, placebo-controlled study, adults 65 years and older were divided into an exercise group and a non-exercise group. Both groups took either 3 g of HMB twice a day or a placebo. The non-exercise group that took HMB showed signs of improved muscle health — but the exercise group's results were even better, improving measurements of muscle function and lean mass.²

Vitamin D3 for hormone health and muscle function

Vitamin D3 promotes healthy muscle function and metabolism.^4,18 Vitamin D also supports healthy mitochondrial function and energy consumption, which are likely to influence muscle strength.³ Vitamin D helps inhibit inflammatory factors to support muscle health as well.¹⁹

Mix with protein or favorite drink

Whether or not you exercise regularly, Muscle Strength & Restore Formula is an excellent addition to your daily health regimen. We've left our formula unflavored, so you can add it to a wide variety of protein shakes, drink mixes, cold water or your favorite beverage.

Magnesium also helps maintain already-healthy blood pressure levels.

Brain & nervous system health

Magnesium plays an important role in the nervous system and helps support healthy brain function. Magnesium can also modulate the signaling of serotonin and other neurotransmitters, and adequate magnesium intake may promote a healthy mood.

Bone health & density

Magnesium, along with calcium and other minerals, is an essential component of a healthy bone matrix. A well-mineralized bone matrix helps maintain strong, healthy bones.

Metabolic health & more

Magnesium intake also promotes a wide range of healthy metabolic factors, serum lipid profiles and more. Magnesium helps protect against oxidative stress, as well.

Produce more ATP with D-ribose

D-ribose, a carbohydrate molecule found in every living organism, is essential in encouraging the production of ATP. In studies of healthy athletes, D-ribose supplementation has been shown to support exercise capacity and recovery. By helping to support cellular energy production, D-ribose may be especially beneficial for promoting heart health.