Iodine is a trace element essential for the production of thyroid hormones, and vitamin K is an essential nutrient that promotes both arterial and bone health.

Iodine is essential for thyroid health

Iodine is a trace element necessary for the production of the thyroid hormones triiodothyronine (T3) and thyroxine (T4).¹ Iodine is abundant in seafood and sea vegetables, but not everyone likes or has access to marine foods, and vegan diets sometimes lack adequate iodine.²

Commercial salt makers add iodine to table salt to make up for this potential deficiency. However, we now know the health risks of eating too much salt, so health-conscious people may miss out on an easy source of iodine. Vitamins D and K with Sea-Iodine™ delivers 1,000 mcg of iodine to support healthy iodine levels.

Vitamin K1 and two different types of K2

Vitamin K helps inhibit calcium buildup in your arteries while promoting healthy calcium absorption into your bone matrix.³ K1 is the most common form of vitamin K in the diet, coming primarily from leafy green vegetables—though vitamin K1 isn’t well absorbed from these foods.

Vitamin K2 is found in cheese, eggs and fermented soybeans. It has been shown to be more bioavailable than K1 and to remain active in the body far longer. The MK-4 and MK-7 forms of vitamin K2 also provide important benefits but have different tissue distributions and bioavailability, so it’s important to take both.^4,5 This formula contains both forms of vitamin K2.

Vitamin D3 for cognitive, bone and immune health

Healthy serum vitamin D levels have been shown to correspond with better cognitive function.^6,7 Vitamin D, along with vitamin K and essential minerals, is necessary for facilitating the transport of calcium into the bone matrix for strong, healthy bones and teeth.⁸ Vitamin D also plays a critical role in healthy immune function.⁹

Some people may need 125 mcg (5,000 IU) to 200 mcg (8,000 IU) of vitamin D3 a day to achieve healthy blood levels of vitamin D. If your multivitamin already delivers 25-75 mcg (1,000–3,000 IU) of vitamin D, adding Vitamins D and K with Sea-Iodine™ may help achieve healthy vitamin D levels.

Vitamin D3 for heart health and blood pressure support

Vitamin D promotes a healthy inflammatory response, supports cardiovascular health and encourages healthy endothelial function. Vitamin D also helps inhibit excess renin levels. Healthy renin levels help maintain healthy blood pressure already within the normal range.¹⁰

Getting enough vitamins D and K and iodine

This vitamin D3 supplement delivers 125 mcg (5,000 IU) of vitamin D3 as cholecalciferol per capsule. We suggest that you take a 25-hydroxy vitamin D blood test after 3 months to assess and adjust your dosage. Your optimal blood levels should be 50–80 ng/ml year-round.

Ensure you get enough of these three essential nutrients with Vitamins D and K with Sea-Iodine™.

Diosmin promotes healthy venous circulation

The complex circulatory system in our legs can weaken with age. But diosmin extract from orange peels has been shown to encourage leg circulation and comfort by helping to maintain tone and elasticity of your leg veins.¹ A double-blind, placebo-controlled study recorded significant improvement in participant-reported leg comfort after just two weeks.²

Healthy, comfortable legs are a beautiful thing

Encouraging healthy, beautiful legs all comes down to your vascular system. In addition to encouraging youthful vascular tone and elasticity, diosmin helps inhibit inflammatory factors to support vascular health, making it an ideal nutrient for healthy, comfortable legs.^3,4

So take care of your aging legs. Try a nutritional supplement that promotes healthy, comfortable and youthful veins, especially in your legs.

Combining black cumin with turmeric

Curcumin is an extract of turmeric. It is a potent nutrient packed with compounds called curcuminoids known to help inhibit inflammation to support healthy heart and joint health, as well as encourage a healthy immune response.^17-21 Our new, proprietary Curcumin Elite™ turmeric extract has 45 times more free curcuminoids and over 270 times more total curcuminoids than standard turmeric extracts.²² That translates to more health benefits for your entire body.

Supports a healthy inflammatory response

Black cumin seed oil has been shown to support the body’s healthy inflammation response by moderating the effect of critical cell-signaling chemicals and hormone-like messengers.^6,8,11,15 Maintaining healthy cell signaling as you age is key to both a healthy inflammatory response as well as immune system function.^2,23

The free curcuminoids in turmeric extract promote the body’s healthy inflammation response as well.^18,19 They also help inhibit inflammatory factors like arachidonic acid, cyclooxygenase, lipoxygenase, and cytokine compounds to support heart health, brain health and whole-body health.^16,24,25

Boosts the immune system

Black cumin seed oil also supports the body’s natural defenses by encouraging optimal function of a healthy immune system. It does this by helping to maintain the vital defensive activities of macrophages and helper T-cells that work together to bolster your immune system.^15,26-30 Curcumin further promotes immune system health and supports a healthy inflammatory response.^31-34

Two essential functions in one supplement

Black Cumin Seed Oil and Curcumin Elite™ from Life Extension® helps you maintain a healthy immune system and promotes a healthy inflammation response with a single, convenient supplement formula. Plus, we’ve recently upgraded our formula to include ultra-bioavailable Curcumin Elite™, which has much better absorption than standard curcumin.

PEA in clinical studies

PEA’s efficacy has been demonstrated in multiple clinical trials. For example: In a controlled trial that randomized 636 patients to placebo or PEA for three weeks, 600 mg of PEA every day significantly improved scores on assessments of relative comfort.

Suggested Use: Chew one or two a day to relieve occasional minor pain and discomfort.

Magnesium also helps maintain already-healthy blood pressure levels.

Brain & nervous system health

Magnesium plays an important role in the nervous system and helps support healthy brain function. Magnesium can also modulate the signaling of serotonin and other neurotransmitters, and adequate magnesium intake may promote a healthy mood.

Bone health & density

Magnesium, along with calcium and other minerals, is an essential component of a healthy bone matrix. A well-mineralized bone matrix helps maintain strong, healthy bones.

Metabolic health & more

Magnesium intake also promotes a wide range of healthy metabolic factors, serum lipid profiles and more. Magnesium helps protect against oxidative stress, as well.

5-MTHF, homocysteine & cardiovascular health

Folate helps maintain healthy homocysteine levels already within the normal range. By helping to inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular health biomarker.¹ And 5-MTHF has been shown to be more bioavailable than folic acid in some studies.^5,7

5-MTHF, homocysteine & cognitive health

5-MTHF's greater bioavailability is especially important for people who don't have enough activity of the enzyme necessary to convert folic acid to its biologically active form. Since people with elevated homocysteine levels have a greater risk of cognitive decline, the increased efficiency of 5-MTHF in supporting healthy folate status is especially crucial for aging individuals. ^8,9

Take alone or with B12 for enhanced effect

The RDA for folate for non-pregnant or lactating adults is 400 mcg a day, but this high-potency formula provides 8500 mcg of this super-bioavailable form of folate. For even greater health benefits, take 5-MTHF folate with methylcobalamin (the active form of vitamin B12), vitamin B6 and/or riboflavin.